NeoGen for menopausal skin

Most women who ask about NeoGen after menopause are not asking about hormones. They are asking why their face looks thinner, why makeup sits differently, and whether anything actually helps. That is a fair question about skin, and it has an honest, partial answer.

What NeoGen is designed to do

NeoGen turns medical grade nitrogen into plasma and applies it across the skin in measured pulses. There are no needles. The outer layer of skin stays in place as a natural dressing while renewal happens underneath, then sheds over the following days. The aim is to support collagen renewal, firmness, texture and tone across the whole treated area in one go, rather than in dots.

That matters for menopausal skin because the change is usually everywhere at once. Oestrogen helps skin build and hold collagen, so when it falls, collagen falls with it. The research on this is covered on the skin changes around menopause page. NeoGen is a collagen-stimulating treatment. Menopause speeds up collagen loss. Those are two separate facts, and joining them is as far as the evidence honestly goes.

What the evidence does and does not show

This is the part most clinic pages skip, so here it is plainly.

• No menopause-specific trial. We have found no published study of NeoGen in menopausal women. The manufacturer, Energist, says itself that NeoGen is not a treatment for menopause or its hormonal causes.
• The landmark plasma study is small. Bogle and colleagues (Archives of Dermatology, 2007) treated eight patients with an earlier plasma device, with no control group and manufacturer funding. They reported a 37% reduction in wrinkles at three months. It tells us plasma can improve lines. It does not tell us how any particular woman will respond.
• The collagen figure belongs to menopause. The often-quoted loss of up to 30% of skin collagen in the first five years after menopause comes from studies of menopause, not of NeoGen.
• An award, with a caveat. The NeoGen device won Best Treatment at the Menopause in Aesthetics Awards 2025. That is recognition of the device, not of this clinic, and the judging criteria are not published, so we treat it as a nod rather than proof.

What we can say is Dr Corcoran’s opinion: that NeoGen suits many women whose skin has changed around menopause. It is his clinical view, formed in clinic, and he would rather you knew it was a view.

What a NeoGen result can look like

Here is a pair that shows lines and skin quality on mature skin, with what produced it written down.

Lighter or stronger: which suits you?

NeoGen is not one setting. The energy is chosen for your skin, and it decides how much changes and how much your week is affected.

• Lighter. For skin that mainly needs its quality lifting. Very little downtime, usually a day or two of redness or flaking.
• Medium. The setting most people mean by NeoGen. Redness, then flaking of the outer layer. Published protocols put it at about three to four days, with most people back at work immediately or the next day.
• Stronger. For deeper concerns. It asks the most of you, with the surface shedding across roughly five to ten days. Dr Corcoran will say so if a lighter setting would get you where you want to be.

How many sessions you need, and how far apart, is planned at your consultation once he has seen your skin.

What NeoGen pairs with

NeoGen leads. The others are added for something it does not do on its own.

If you are comparing NeoGen with Profhilo specifically: they do different jobs. NeoGen works on the skin’s surface and renewal response. Profhilo is an injectable that spreads hyaluronic acid through the skin for hydration and quality. Many women end up with both, which is why they sit side by side in the table.

What NeoGen does not do

It does not treat menopause, hot flushes, sleep or mood, and it does not replace anything your GP offers. It does not replace lost volume, and it does not lift deep laxity the way HIFU or Endolift can. A good plan says so before you pay for it.

Common questions