PolynucleotideTreatment
A natural, DNA-derived injectable treatment that works at a cellular level to reduce inflammation, stimulate collagen production and restore long-term skin health.
What are Polynucleotides?
Polynucleotides are naturally occurring DNA fragments that stimulate cellular repair, reduce inflammation and promote collagen synthesis when injected into the skin.
Nature’s repair mechanism, concentrated and delivered precisely.
Polynucleotides (also known as PDRN) are derived from purified salmon DNA, which shares a high degree of compatibility with human DNA. When injected into the skin, they are recognised and absorbed by skin cells, where they act as signalling molecules that activate the skin’s own repair and regeneration pathways.
Unlike many injectable treatments that primarily add volume or hydration, polynucleotides work at a deeper cellular level, reducing oxidative stress, dampening inflammation, stimulating fibroblast activity and supporting long-term tissue health.
Polynucleotides are particularly valuable for patients with chronically inflamed, damaged or sensitised skin, including those with acne-prone skin, rosacea, sun damage or post-inflammatory pigmentation.
They are also highly effective as a standalone regenerative treatment for patients who want to improve overall skin health, reduce fine lines and achieve a calmer, clearer complexion over time.
How do polynucleotides work?
A comfortable injectable treatment with no significant downtime and progressively improving results over a short course of sessions.
Results and Benefits
Polynucleotides produce progressive improvements in skin health, texture and long-term cellular vitality.
Everything you need to know
Honest answers to the questions we hear most often before patients book.
Why The Plasma Doctor
A medically led clinic in Warrington, North West England. Every treatment is carried out by Dr James Corcoran with clinical precision and genuine care.
Medically Led
Every treatment is administered by Dr James Corcoran personally. A qualified medical doctor with specialist aesthetic training.
Honest Advice
We will tell you honestly whether this is the right treatment for your concern. If it is not, we will tell you what is. We never oversell.
Genuine Technology
We use only clinically validated equipment backed by peer-reviewed evidence. Not replicas, not imitations.
Personalised Plans
No two patients are the same. Your treatment plan is built around your concerns, goals and lifestyle, not a standard package.
Ongoing Support
We are with you throughout your treatment journey. From your first consultation to your final review, we are here to help.
North West Based
Based in Warrington with easy access from Manchester, Liverpool and across the North West.
What our patients say
Experts using outstanding products and devices. Why go anywhere else?
The treatment was totally pain free and the results beyond my expectations. I would recommend you go and see for yourself. Absolutely brilliant.
I am 82 years old and have never undergone cosmetic surgery. I am truly overwhelmed by the results and cannot believe the transformation in my face.
Book your polynucleotide consultation today
Your consultation with Dr James Corcoran is the starting point. We will assess your skin, explain what polynucleotides can achieve for your concerns and build a personalised plan.
