Polynucleotide TreatmentNature’s repair mechanism, concentrated.
A natural, DNA-derived injectable treatment that works at a cellular level to reduce inflammation, stimulate collagen production and restore long-term skin health. Delivered personally by Dr James Corcoran.
What are polynucleotides?
Polynucleotides are naturally occurring DNA fragments that stimulate cellular repair, reduce inflammation and promote collagen synthesis when injected into the skin.
Polynucleotides (also known as PDRN) are derived from purified salmon DNA, which shares a high degree of compatibility with human DNA. When injected into the skin, they are recognised and absorbed by skin cells, where they act as signalling molecules that activate the skin’s own repair and regeneration pathways.
Unlike many injectable treatments that primarily add volume or hydration, polynucleotides work at a deeper cellular level, reducing oxidative stress, dampening inflammation, stimulating fibroblast activity and supporting long-term tissue health.
Polynucleotides are particularly valuable for patients with chronically inflamed, damaged or sensitised skin, including those with acne-prone skin, rosacea, sun damage or post-inflammatory pigmentation.
Who it suits
Highly effective as a standalone regenerative treatment for patients who want to improve overall skin health, reduce fine lines and achieve a calmer, clearer complexion over time.
How do polynucleotides work?
A comfortable injectable treatment with no significant downtime and progressively improving results over a short course of sessions.
Is this treatment right for you?
Dr Corcoran confirms suitability properly at consultation, but this is a fair starting point.
- You have chronically inflamed, sensitised or damaged skin
- You have acne-prone skin, rosacea or post-inflammatory pigmentation
- You want a completely natural, DNA-derived treatment
- You want to support long-term skin health, not just surface appearance
- Your main concern is volume loss rather than skin health, where filler may serve you better
- You want an immediate, one-session result
- You have a known allergy to fish products
- You are pregnant or breastfeeding
Results and benefits
Polynucleotides produce progressive improvements in skin health, texture and long-term cellular vitality.
Everything you need to know
Honest answers to the questions we hear most often before patients book.
Why The Plasma Doctor for polynucleotides?
A medically led clinic in Warrington. Every treatment carried out by Dr James Corcoran with clinical precision and genuine care.
What our patients say
Experts using outstanding products and devices. Why go anywhere else?
The treatment was totally pain free and the results beyond my expectations. Absolutely brilliant.
I am 82 years old and have never undergone cosmetic surgery. I am truly overwhelmed by the results.
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Book your polynucleotide consultation today
Your consultation with Dr James Corcoran is the starting point. We will assess your skin, explain what polynucleotides can achieve and build a personalised plan.
